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Solid Tumors
This category includes Neuroblastoma, Rhabdomyosarcoma, Osteogenic Sarcoma, Ewing’s Sarcoma/Primitive Neuroectodermal Tumor (PNET), other sarcomas, Wilms Tumor, Hepatoblastoma, Retinoblastoma, Desmoplastic Small Round Cell Tumor, Germ Cell Tumors (testicular, ovarian, other), other solid tumors.

Trials

European Ewing Tumor Working Initiative of National Groups Ewing Tumour Studies 1999 (EURO-E.W.I.N.G.99) (AEWS0331)
Phase
: III Site: Phoenix Status: Open



A Children's Oncology Group protocol for Collecting and Banking Ewing Sarcoma Specimens (AEWS07B1)
Phase
: Biology Site: Phoenix Status: Open



A Randomized Phase II Study of Bevacizumab Combined withi Vincristine, Topotecan and Cyclophosphamide in Patients with First Recurrent Ewing Sarcoma
Phase
: II Site: Phoenix Status: Open



A Randomized Trial of the European and American Osteosarcoma Study Group to Optimize Treatment Strategies for Resectable Osteosarcoma Based on Histologic Response to Pre-Operative Chemotherapy (EURAMOS 1, AOST0331)
Phase
: III Site: Phoenix Status: Open



A Children's Oncology Group Protocol for Collecting and Banking Osteosarcoma Specimens (AOST06B1)
Phase
: Biology Site: Phoenix Status: Open



Vincristine, D-Actinomycin,and lower doses of Cyclophosphamide with or without Radiation Therapy for patients with newly diagnosed, low-risk Embryonal/Botryoid/Spindle Cell Rhabdomyosarcoma (ARST0331)
Phase
: III Site: Phoenix Status: Open



Randomized Study of Vincristine, Dactinomycin and Cyclophosphamide (VAC) versus VAC Alternating with Vincristine and Irinotecan (VI) for Patients with Intermediate-Risk Rhabdomyosarcoma (RMS)(ARST0531)
Phase
: III Site: Phoenix Status: Active



A Pilot Study to Evaluate Novel Agents (Temozolomide and Cixutumumab [IMC-A12, Anti-IGF-IR Monoclonal Antibody, IND #100947, NSC #742460]) in Combination with Intensive Multi-Agent Interval Compressed Therapy for Patients with High-Risk Rhabdomyosarcoma (ARST08P1)
Phase
: Pilot Site: Phoenix Status: Open



Risk-Based Treatment for Pediatric Non-Rhabdomyosarcoma Soft Tissue Sarcomas (NRSTS, ARST0332)
Phase
: III Site: Phoenix Status: Open



Neuroblastoma Biology Studies (ANBL00B1)
Phase
: Biology Site: Phoenix Status: Open



Randomized Study of Chimeric Anti-GD2 in High Risk Neuroblastoma Following Myeloablative Therapy and Autologous Stem Cell Rescue (ANBL0032)
Phase
: II Site: Phoenix Status: Open



Response and Biology-based Therapy for Intermediate-risk Neuroblastoma (ANBL0531)
Phase
: III Site: Phoenix Status: Open



Phase III Randomized Trial of Single vs. Tandem Myeloablative as Consolidation Therapy for High-Risk Neuroblastoma (ANBL0532)
Phase
: III Site: Phoenix Status: Open



A Randomized, Phase II Study of Monoclonal Antibody 3F8 plus Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Compared to 13-cis-Retinoic acid plus GM-CSF in High Risk Stage 4, Primary Refractory Neuroblastoma Patients (3F8-NB-201)
Phase
: II Site: Phoenix Status: Open



Renal Tumors Classification, Biology, and Banking Study (AREN03B2)
Phase
: Biology Site: Phoenix Status: Open



Treatment for Very Low and Standard Risk Favorable Histology Wilms Tumor (AREN0532)
Phase
: III Site: Phoenix Status: Active



Treatment of High Risk Renal Tumors (AREN0321)
Phase
: II Site: Phoenix Status: Open



Treatment of Newly Diagnosed Higher Risk Favorable Histology Wilms Tumors (AREN0533)
Phase
: III Site: Phoenix Status: Active



National Wilms Tumor Late Effects Study (COG-4941L)
Phase
: Registry Site: Phoenix Status: Open



Reduced Therapy in the Treatment of Children with Low and Intermediate Risk Extracranial Germ Cell Tumors (AGCT0132)
Phase
: III Site: Phoenix Status: Open



Low Birth Weight and Other Risk Factors for Hepatoblastoma: A Groupwide Protocol (AEPI04C1)
Phase
: Epidemiology Site: Phoenix Status: Open



A COG Soft Tissue Sarcoma Biology and Banking Protocol (D9902)
Phase
: Biology Site: Phoenix Status: Open



A Children’s Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors (ABTR01B1)
Phase
: Biology Site: Phoenix Status: Open



Characterization of immune phenotype, dendritic cell generation, and growth of tumor cells in patients with newly diagnosed and relapsed pediatric high risk sarcomas (PCH 09-092)
Phase
: Biology Site: Phoenix Status: Open



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